HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23353999
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 221
+	Hs
		516355 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		582544 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		516635 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		1020306 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		516339 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27
+	Hs
		516484 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		1020249 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79
+	Hs
		1288621 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRSF8_HUMAN (1-183): 4.13e-29: 111: 63.39
+	Hs
		474034 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAB4L_HUMAN (15-92): 1.09e-20: 90.5: 26.92
+	Hs
		516495 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37
+	Hs
		516689 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP3_HUMAN (15-221): 2.48e-24: 101: 16.91
+	Hs
		516730 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76
+	Hs
		474021 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		PAB4L_HUMAN (15-92): 1.09e-20: 90.5: 26.92
+	Hs
		1055876 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		ELAV3_HUMAN (115-195): 1.55e-11: 64.6: 11.11
+	Mm
		665745 PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55		TIA1_MOUSE (7-184): 8.63e-17: 79.6: 11.67
+	Hs
		1119141 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAP1L_HUMAN (104-193): 4.46e-11: 63.5: 8.89
+	Hs
		516471 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TIAR_HUMAN (9-167): 1.19e-15: 76.6: 9.26