HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: KPCZ (Q05513)
Protein kinase C zeta type (EC 2.7.11.13) (nPKC-zeta)
Gene: PRKCZ

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9388266
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0043560 - insulin receptor substrate binding GO:0046627 - negative regulation of insulin receptor signaling pathway GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 592
+	Hs
		582536 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Hs
		582149 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		KS6A3_HUMAN (168-539): 2.67e-105: 335: 20.47
+	Rn
		1144336 PABP1_RAT (222-482): 5.13e-43: 167: 15.55		AKT3_RAT (171-582): 3.93e-152: 447: 36.53
+	Hs
		516724 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		KS6B2_HUMAN (237-590): 1.59e-143: 425: 36.59
+	Hs
		116962 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SGK1_HUMAN (199-583): 7.41e-144: 424: 38.36
+	Hs
		516351 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		568649 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06
+	Hs
		568550 ELAV4_HUMAN (464-709): 5.73e-44: 164: 18.82		KAPCA_HUMAN (219-578): 5.07e-143: 419: 33.06