HitPredict

Interactor 1: NUCL (P19338)
Nucleolin (Protein C23)
Gene: NCL

Interactor 2: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0044547 - DNA topoisomerase binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 710 Hs			1 248
+	Hs
		516355 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67
+	Hs
		582224 NUCL_HUMAN (1-650): 8.84e-98: 318: 100.00		SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53
+	Hs
		1028593 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25
+	Hs
		516493 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25
+	Hs
		992875 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00
+	Hs
		516478 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF1_HUMAN (1-235): 1.04e-49: 165: 100.00
+	Hs
		516635 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67
+	Hs
		516339 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67
+	Hs
		516689 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP3_HUMAN (8-203): 1.09e-33: 129: 16.18
+	Hs
		1119141 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAP1L_HUMAN (17-148): 9.11e-22: 95.4: 18.80
+	Hs
		516466 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53
+	Hs
		474034 PABP5_HUMAN (233-555): 7.34e-51: 183: 17.20		PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48
+	Sc
		376562 PABP_YEAST (181-555): 3.61e-53: 194: 17.47		PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73
+	Zm
		8143 A0A1D6ELH4_MAIZE (204-491): 4.85e-38: 152: 15.53		A0A1D6ELH4_MAIZE (5-246): 1.03e-23: 101: 14.58
+	Hs
		474021 PABP4_HUMAN (222-488): 1.86e-42: 165: 14.88		PAB4L_HUMAN (17-92): 5.07e-19: 86.6: 19.48
+	Hs
		516495 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67
+	Hs
		516471 PABP1_HUMAN (222-482): 4.4e-43: 167: 15.55		TIAR_HUMAN (113-202): 2.85e-10: 61.5: 12.63
+	Mm
		665745 PABP1_MOUSE (222-482): 5.43e-43: 167: 15.55		TIA1_MOUSE (115-203): 5.51e-10: 60.8: 11.70