Interactor 1: SYTC2 (A2RTX5)
Threonine--tRNA ligase 2, cytoplasmic (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase protein 3)
Gene: TARS3

Interactor 2: SYTM (Q9BW92)
Threonine--tRNA ligase, mitochondrial (EC 6.1.1.3) (Threonyl-tRNA synthetase) (ThrRS) (Threonyl-tRNA synthetase-like 1)
Gene: TARS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.61 1.00 0.783

The method score is based on:

Property Details
Experiments 32296183, unassigned1304
Identification Methods two hybrid, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains HGTP_anticodon~HGTP_anticodon, HGTP_anticodon~tRNA-synt_2b, TGS~TGS, TGS~tRNA_SAD, tRNA-synt_2b~tRNA-synt_2b
Common GO terms GO:0004829 - threonine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0006435 - threonyl-tRNA aminoacylation
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 802
Hs

1 718
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Last updated: 15 Jul 2024