HitPredict

Interactor 1: HXK1 (P19367)
Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A)
Gene: HK1

Interactor 2: HXK1 (P19367)
Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A)
Gene: HK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 29568061, 10574795, 28054552
Identification Methods proximity labelling technology, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hexokinase_1~Hexokinase_1, Hexokinase_1~Hexokinase_2, Hexokinase_2~Hexokinase_2
Common GO terms GO:0001678 - intracellular glucose homeostasis
GO:0002720 - positive regulation of cytokine production involved in immune response
GO:0004340 - glucokinase activity
GO:0004396 - hexokinase activity
GO:0005524 - ATP binding
and 21 others

more...
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 917
Hs

1 917
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024