HitPredict

Interactor 1: HXK1 (P19367)
Hexokinase-1 (EC 2.7.1.1) (Brain form hexokinase) (Hexokinase type I) (HK I) (Hexokinase-A)
Gene: HK1

Interactor 2: VDAC1 (P21796)
Voltage-dependent anion-selective channel protein 1 (VDAC-1) (hVDAC1) (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM)
Gene: VDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	22304920, 35271311
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0045121 - membrane raft
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 917 Hs			1 283
+	Hs
		583383 HXK1_HUMAN (1-917): 0: 1386: 100.00		VDAC3_HUMAN (1-283): 1.29e-105: 310: 67.49
+	Rn
		404410 HXK1_RAT (1-916): 0: 1363: 92.80		VDAC1_RAT (1-283): 2.26e-110: 322: 98.59
+	Hs
		601184 HXK2_HUMAN (1-916): 0: 1363: 73.47		VDAC1_HUMAN (1-283): 1.37e-110: 322: 100.00
+	Hs
		856259 HXK2_HUMAN (1-916): 0: 1363: 73.47		VDAC3_HUMAN (1-283): 1.29e-105: 310: 67.49
+	Rn
		654991 HXK2_RAT (1-916): 0: 1344: 72.93		VDAC1_RAT (1-283): 2.26e-110: 322: 98.59
+	At
		1114896 HXK1_ARATH (22-467): 0: 539: 33.33		VDAC1_ARATH (1-282): 7.78e-84: 254: 21.75