HitPredict

Interactor 1: RPB3 (P19387)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31)
Gene: POLR2C

Interactor 2: GPN3 (Q9UHW5)
GPN-loop GTPase 3 (ATP-binding domain 1 family member C)
Gene: GPN3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.638

Property	Details
Experiments	26186194, 28514442, 33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 275 Hs			1 284
+	Hs
		583586 RPB3_HUMAN (1-275): 6.89e-138: 391: 100.00		GPN2_HUMAN (4-254): 1.73e-132: 379: 42.13
+	Hs
		169985 RPAC1_HUMAN (3-269): 1.2e-110: 325: 25.90		GPN3_HUMAN (1-284): 1.23e-155: 437: 100.00
+	Hs
		583591 RPB3_HUMAN (1-275): 6.89e-138: 391: 100.00		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		558272 RPB3_YEAST (4-271): 9.52e-107: 313: 45.06		GPN3_YEAST (1-268): 5.79e-122: 351: 43.17
+	Sc
		558300 RPB3_YEAST (4-271): 9.52e-107: 313: 45.06		GPN2_YEAST (3-254): 8.37e-105: 310: 34.35
+	Hs
		169961 RPAC1_HUMAN (3-269): 1.2e-110: 325: 25.90		GPN1_HUMAN (3-251): 6.08e-98: 293: 25.40
+	Sc
		558136 RPB3_YEAST (4-271): 9.52e-107: 313: 45.06		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34
+	Sc
		429734 RPAC1_YEAST (3-261): 1.36e-96: 288: 25.42		GPN1_YEAST (1-284): 1.16e-86: 265: 22.34