HitPredict

Interactor 1: RPAB1 (P19388)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)
Gene: POLR2E

Interactor 2: RPB9 (P36954)
DNA-directed RNA polymerase II subunit RPB9 (RNA polymerase II subunit B9) (DNA-directed RNA polymerase II subunit I) (RNA polymerase II 14.5 kDa subunit) (RPB14.5)
Gene: POLR2I

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	35271311, 28514442, 24981860
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RNA_pol_Rpb5_N~TFIIS_C
Common GO terms	GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005665 - RNA polymerase II, core complex GO:0006366 - transcription by RNA polymerase II
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 210 Hs			1 125
+	Hs
		583845 RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00		RPC10_HUMAN (14-125): 6.76e-35: 117: 26.79
+	Hs
		583829 RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00		RPA12_HUMAN (12-125): 2.72e-23: 89: 16.67
+	Sc
		593112 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPB9_YEAST (11-124): 3.78e-38: 126: 43.86
+	Sc
		593185 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPC10_YEAST (14-125): 3.41e-32: 111: 27.43
+	Sc
		593120 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPA12_YEAST (11-124): 1.49e-22: 87.1: 15.70
+	Sc
		425453 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		TFS2_YEAST (41-124): 2.88e-19: 82.5: 17.86