HitPredict

Interactor 1: CD53 (P19397)
Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Tetraspanin-25) (Tspan-25) (CD antigen CD53)
Gene: CD53

Interactor 2: VAMP3 (Q15836)
Vesicle-associated membrane protein 3 (VAMP-3) (Cellubrevin) (CEB) (Synaptobrevin-3)
Gene: VAMP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 219 Hs			1 100
+	Hs
		306755 CD53_HUMAN (1-219): 5.58e-59: 186: 100.00		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		887862 CD81_HUMAN (4-214): 3.1e-48: 159: 28.26		VAMP3_HUMAN (1-81): 1.11e-25: 93.5: 100.00
+	Hs
		306781 CD81_HUMAN (4-214): 3.1e-48: 159: 28.26		VAMP5_HUMAN (11-80): 1.96e-20: 80.4: 38.57
+	Hs
		237795 TSN3_HUMAN (1-209): 1.08e-39: 138: 26.27		VAMP7_HUMAN (7-79): 4.38e-23: 90: 31.51