HitPredict

Interactor 1: ELK1 (P19419)
ETS domain-containing protein Elk-1
Gene: ELK1

Interactor 2: MK09 (P45984)
Mitogen-activated protein kinase 9 (MAP kinase 9) (MAPK 9) (EC 2.7.11.24) (JNK-55) (Stress-activated protein kinase 1a) (SAPK1a) (Stress-activated protein kinase JNK2) (c-Jun N-terminal kinase 2)
Gene: MAPK9

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.682

Property	Details
Experiments	8654373, 17875713, 8846788
Identification Methods	enzymatic study, two hybrid, in-gel kinase assay
Interaction Type	direct interaction, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 424
+	Hs
		584226 ELK1_HUMAN (1-428): 8.38e-56: 192: 100.00		MK10_HUMAN (1-424): 1.16e-155: 449: 84.04
+	Hs
		584217 ELK1_HUMAN (1-428): 8.38e-56: 192: 100.00		MK08_HUMAN (1-424): 1.17e-153: 443: 80.80
+	Hs
		657807 ELK4_HUMAN (1-427): 1.75e-29: 120: 30.68		MK08_HUMAN (1-424): 1.17e-153: 443: 80.80
+	Hs
		800726 ETV1_HUMAN (4-90): 1.76e-22: 101: 60.92		MK08_HUMAN (1-424): 1.17e-153: 443: 80.80
+	Hs
		542010 ETS1_HUMAN (5-98): 2.37e-37: 142: 56.38		MK07_HUMAN (16-385): 3.24e-132: 401: 37.53
+	Hs
		840374 ERF_HUMAN (5-251): 2.75e-42: 158: 26.82		MK14_HUMAN (4-375): 9.3e-130: 379: 48.00
+	Hs
		542017 ETS1_HUMAN (5-98): 2.37e-37: 142: 56.38		MK14_HUMAN (4-375): 9.3e-130: 379: 48.00
+	Hs
		840437 ETV1_HUMAN (4-90): 1.76e-22: 101: 60.92		MK14_HUMAN (4-375): 9.3e-130: 379: 48.00
+	Hs
		584208 ELK1_HUMAN (1-428): 8.38e-56: 192: 100.00		MK01_HUMAN (15-364): 1.35e-82: 259: 40.50
+	Mm
		785338 ELK1_MOUSE (1-428): 2.58e-51: 180: 85.12		MK03_MOUSE (20-370): 8.49e-83: 260: 40.56
+	Mm
		785336 ELK1_MOUSE (1-428): 2.58e-51: 180: 85.12		MK01_MOUSE (15-364): 3.12e-82: 258: 40.22
+	Hs
		658856 ERF_HUMAN (5-251): 2.75e-42: 158: 26.82		MK01_HUMAN (15-364): 1.35e-82: 259: 40.50
+	Rn
		88640 D3ZJW0_RAT (5-251): 2e-42: 158: 26.82		MK03_RAT (20-364): 1.73e-82: 259: 40.96
+	Rn
		78170 B5DEX5_RAT (5-107): 5.67e-44: 152: 44.66		MK03_RAT (20-364): 1.73e-82: 259: 40.96
+	Hs
		541984 ETS1_HUMAN (5-98): 2.37e-37: 142: 56.38		MK01_HUMAN (15-364): 1.35e-82: 259: 40.50
+	Hs
		657805 ELK4_HUMAN (1-427): 1.75e-29: 120: 30.68		MK01_HUMAN (15-364): 1.35e-82: 259: 40.50
+	Hs
		658826 ETV3_HUMAN (5-418): 3.53e-28: 118: 19.24		MK01_HUMAN (15-364): 1.35e-82: 259: 40.50