HitPredict

Interactor 1: ELK1 (P19419)
ETS domain-containing protein Elk-1
Gene: ELK1

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.594

Property	Details
Experiments	25814554, unassigned1126
Identification Methods	two hybrid, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 304
+	Hs
		785341 ELK3_HUMAN (1-427): 1.26e-32: 129: 35.34		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		562622 ELK1_HUMAN (1-428): 8.38e-56: 192: 100.00		PLCG2_HUMAN (1-301): 1.03e-25: 109: 15.89
+	Hs
		203218 SYNJ1_HUMAN (52-427): 1.79e-31: 129: 11.83		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		785349 ELK3_HUMAN (1-427): 1.26e-32: 129: 35.34		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		275177 ETV5_HUMAN (4-90): 2.93e-21: 97.8: 59.77		GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17
+	Hs
		203208 SYNJ1_HUMAN (52-427): 1.79e-31: 129: 11.83		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		203228 SYNJ1_HUMAN (52-427): 1.79e-31: 129: 11.83		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		557627 ELK3_HUMAN (1-427): 1.26e-32: 129: 35.34		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		203241 SYNJ1_HUMAN (52-427): 1.79e-31: 129: 11.83		SH3K1_HUMAN (114-192): 4.08e-10: 62.5: 22.22