HitPredict

Interactor 1: ELK1 (P19419)
ETS domain-containing protein Elk-1
Gene: ELK1

Interactor 2: PRKDC (P78527)
DNA-dependent protein kinase catalytic subunit (DNA-PK catalytic subunit) (DNA-PKcs) (EC 2.7.11.1) (DNPK1) (p460)
Gene: PRKDC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	31980649, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 4128
+	Hs
		507398 ERG_HUMAN (5-171): 7.48e-40: 150: 37.06		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		541998 ETS1_HUMAN (5-98): 2.37e-37: 142: 56.38		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		840432 ETV1_HUMAN (4-90): 1.76e-22: 101: 60.92		PRKDC_HUMAN (1-4128): 0: 6819: 100.00
+	Hs
		692204 ELF1_HUMAN (4-362): 1.15e-33: 134: 22.40		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		1304913 ELF4_HUMAN (3-408): 2.19e-31: 128: 19.71		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		1077626 ELF2_HUMAN (3-346): 6.56e-30: 124: 20.23		TRRAP_HUMAN (2754-4128): 0: 828: 15.88
+	Hs
		840434 ETV1_HUMAN (4-90): 1.76e-22: 101: 60.92		ATR_HUMAN (3377-4128): 2.05e-122: 438: 19.28