HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	30561431, 30420664
Identification Methods	affinity chromatography technology, virotrap
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006954 - inflammatory response GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050729 - positive regulation of inflammatory response
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 636
+	Mm
		626882 TNR1A_MOUSE (1-445): 4.25e-127: 377: 64.37		TNIP1_MOUSE (1-636): 1.34e-64: 226: 82.28
+	Hs
		584332 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		584331 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		1063815 LAMA4_HUMAN (33-444): 1.12e-15: 82: 14.38		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		591272 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48
+	Hs
		591271 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		MYH9_HUMAN (267-566): 1.17e-09: 63.8: 13.33
+	Hs
		725260 TR10D_HUMAN (38-345): 3.39e-33: 130: 15.85		MYH10_HUMAN (210-571): 5.78e-13: 74.6: 10.48