HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: RN138 (Q8WVD3)
E3 ubiquitin-protein ligase RNF138 (EC 2.3.2.27) (Nemo-like kinase-associated RING finger protein) (NLK-associated RING finger protein) (hNARF) (RING finger protein 138) (RING-type E3 ubiquitin transferase RNF138)
Gene: RNF138

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 455 Hs			1 245
+	Hs
		584509 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		584394 TNR1A_HUMAN (1-455): 1.34e-147: 430: 100.00		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69
+	Hs
		1024787 EDAR_HUMAN (27-450): 4e-77: 249: 14.32		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69
+	Hs
		738686 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		RN166_HUMAN (5-244): 4.23e-40: 140: 29.58
+	Hs
		738713 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		RN114_HUMAN (16-241): 4.34e-36: 129: 30.53
+	Hs
		129536 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		TRAF5_HUMAN (8-245): 3.76e-30: 119: 15.06
+	Mm
		192585 TNR11_MOUSE (43-368): 3.3e-58: 203: 16.48		TRAF6_MOUSE (12-227): 4.49e-33: 127: 15.77
+	Hs
		738661 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69
+	Hs
		738696 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		TRIM4_HUMAN (10-142): 6.25e-29: 115: 13.33
+	Hs
		738694 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		TRAF4_HUMAN (8-207): 1.85e-27: 111: 13.14
+	Mm
		192584 TNR11_MOUSE (43-368): 3.3e-58: 203: 16.48		TRAF5_MOUSE (8-245): 3.94e-29: 116: 15.06
+	Mm
		192587 TNR11_MOUSE (43-368): 3.3e-58: 203: 16.48		TRAF3_MOUSE (2-245): 1.13e-28: 115: 14.69
+	Mm
		648955 TNR5_MOUSE (43-326): 7e-52: 178: 20.63		TRAF6_MOUSE (12-227): 4.49e-33: 127: 15.77
+	Mm
		838552 TNR3_MOUSE (20-331): 1.61e-54: 189: 23.44		TRAF5_MOUSE (8-245): 3.94e-29: 116: 15.06
+	Mm
		838553 TNR3_MOUSE (20-331): 1.61e-54: 189: 23.44		TRAF3_MOUSE (2-245): 1.13e-28: 115: 14.69
+	Hs
		1377881 TNR11_HUMAN (43-368): 2.49e-47: 174: 16.43		TRAF6_HUMAN (12-245): 1.55e-33: 128: 16.25
+	Hs
		129607 TNR11_HUMAN (43-368): 2.49e-47: 174: 16.43		TRAF5_HUMAN (8-245): 3.76e-30: 119: 15.06
+	Hs
		632261 TNR6_HUMAN (1-167): 7.65e-47: 166: 23.21		TRI26_HUMAN (4-239): 2.73e-33: 127: 15.64
+	Mm
		648958 TNR5_MOUSE (43-326): 7e-52: 178: 20.63		TRAF3_MOUSE (2-245): 1.13e-28: 115: 14.69
+	Hs
		1024798 TNR11_HUMAN (43-368): 2.49e-47: 174: 16.43		TRAF3_HUMAN (2-245): 1.23e-28: 115: 14.69