Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: FAN (Q92636)
Protein FAN (Factor associated with neutral sphingomyelinase activation) (Factor associated with N-SMase activation)
Gene: NSMAF

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.72 0.60 0.661

The method score is based on:

Property Details
Experiments 8808629, 10187805, 17599063
Identification Methods two hybrid, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0034250 - positive regulation of amide metabolic process
GO:0045834 - positive regulation of lipid metabolic process
GO:1905038 - regulation of membrane lipid metabolic process
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 455
Hs

1 917
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024