HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: RNF31 (Q96EP0)
E3 ubiquitin-protein ligase RNF31 (EC 2.3.2.31) (HOIL-1-interacting protein) (HOIP) (RING finger protein 31) (RING-type E3 ubiquitin transferase RNF31) (Zinc in-between-RING-finger ubiquitin-associated domain protein)
Gene: RNF31

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	0.60	0.676

Property	Details
Experiments	26670046, 27552911, 27591049, 30420664
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042742 - defense response to bacterium GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 1072
+	Mm
		626875 TNR1A_MOUSE (1-445): 4.25e-127: 377: 64.37		RNF31_MOUSE (1-1072): 0: 1083: 85.54
+	Hs
		738689 TNR3_HUMAN (11-328): 5.78e-63: 211: 24.85		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		591388 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		RNF31_HUMAN (1-1072): 0: 1111: 100.00
+	Hs
		639627 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		RNF31_HUMAN (1-1072): 0: 1111: 100.00