HitPredict

Interactor 1: TNR1A (P19438)
Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)]
Gene: TNFRSF1A

Interactor 2: CDC6 (Q99741)
Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)
Gene: CDC6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 455 Hs			1 560
+	Hs
		1306126 EDAR_HUMAN (27-450): 4e-77: 249: 14.32		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		121527 TR10A_HUMAN (51-445): 8.24e-66: 220: 17.57		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		591396 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		661053 TNR8_HUMAN (49-211): 1.15e-20: 96.6: 24.10		CDC6_HUMAN (1-560): 1.83e-166: 486: 100.00
+	Hs
		591323 TNR1B_HUMAN (7-287): 3.18e-45: 165: 19.86		ORC1_HUMAN (4-548): 3.74e-94: 308: 22.62
+	Hs
		217776 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49
+	Hs
		639556 TNR5_HUMAN (38-315): 1.92e-46: 163: 19.64		RFC5_HUMAN (162-518): 3.37e-64: 215: 17.04
+	Hs
		217760 TNF6B_HUMAN (31-145): 1.19e-10: 64.2: 19.13		ORC4_HUMAN (143-552): 5.24e-66: 222: 14.49