HitPredict

Interactor 1: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Interactor 2: TNIP1 (Q15025)
TNFAIP3-interacting protein 1 (A20-binding inhibitor of NF-kappa-B activation 1) (ABIN-1) (HIV-1 Nef-interacting protein) (Nef-associated factor 1) (Naf1) (Nip40-1) (Virion-associated nuclear shuttling protein) (VAN) (hVAN)
Gene: TNIP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36574265
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 782 Hs			1 636
+	Hs
		1064002 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		571461 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		134051 DDX3X_HUMAN (204-677): 1.56e-104: 337: 11.22		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		181699 DDX3Y_HUMAN (201-677): 7.95e-102: 329: 10.85		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		1064132 DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		1064188 DDX18_HUMAN (189-720): 1.43e-85: 287: 14.88		TNIP1_HUMAN (1-636): 6.24e-78: 262: 100.00
+	Hs
		1328107 DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19		SMC3_HUMAN (278-527): 2.28e-43: 169: 25.09
+	Mm
		50519 A1L333_MOUSE (198-712): 5.07e-107: 342: 12.87		FTM_MOUSE (17-526): 3.12e-25: 113: 15.30
+	Mm
		1143618 DDX3X_MOUSE (243-677): 9.71e-104: 334: 11.40		FTM_MOUSE (17-526): 3.12e-25: 113: 15.30
+	Hs
		149137 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		1255641 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12
+	Hs
		148373 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		571524 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		RBCC1_HUMAN (161-525): 5.86e-15: 81.1: 17.12
+	Hs
		1271642 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Hs
		148153 DDX3Y_HUMAN (201-677): 7.95e-102: 329: 10.85		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		571580 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		CP250_HUMAN (63-566): 3.97e-11: 68.8: 11.57
+	Hs
		149273 DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		1147658 DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19		FTM_HUMAN (66-531): 2.14e-09: 62.7: 12.89
+	Hs
		149298 DDX31_HUMAN (204-653): 9.57e-87: 294: 13.92		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12
+	Hs
		149351 DDX18_HUMAN (189-720): 1.43e-85: 287: 14.88		CTRO_HUMAN (51-557): 1.5e-16: 86.2: 14.12