Interactor 1: GSH1 (P19468)
Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase)
Gene: Gclc
Interactor 2: GSH0 (P48508)
Glutamate--cysteine ligase regulatory subunit (GCS light chain) (Gamma-ECS regulatory subunit) (Gamma-glutamylcysteine synthetase regulatory subunit) (Glutamate--cysteine ligase modifier subunit)
Gene: Gclm
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.33 | 0.60 | 0.445 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9675072 |
| Identification Methods | biochemical |
| Interaction Type | association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0004357 - glutamate-cysteine ligase activity GO:0006534 - cysteine metabolic process GO:0006536 - glutamate metabolic process GO:0006749 - glutathione metabolic process GO:0006750 - glutathione biosynthetic process and 17 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Mm |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
| + | Dm |  |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
