HitPredict

Interactor 1: RO52 (P19474)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: TRIM21

Interactor 2: MAT1 (P51948)
CDK-activating kinase assembly factor MAT1 (CDK7/cyclin-H assembly factor) (Cyclin-G1-interacting protein) (Menage a trois) (RING finger protein 66) (RING finger protein MAT1) (p35) (p36)
Gene: MNAT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	22493164
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0008270 - zinc ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 309
+	Hs
		851289 TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00
+	Hs
		851296 TRI17_HUMAN (1-471): 6.2e-124: 371: 35.39		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00
+	Hs
		851269 TRIML_HUMAN (1-469): 6.24e-122: 366: 36.86		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00
+	Hs
		851282 TRIM5_HUMAN (1-466): 9.08e-121: 363: 40.04		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00
+	Hs
		851279 TRI34_HUMAN (1-466): 2.36e-108: 331: 41.60		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00
+	Hs
		851242 TRI26_HUMAN (1-354): 6.86e-55: 193: 34.73		MAT1_HUMAN (1-309): 6.09e-158: 444: 100.00