HitPredict

Interactor 1: RO52 (P19474)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: TRIM21

Interactor 2: GBRL2 (P60520)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Ganglioside expression factor 2) (GEF-2) (General protein transport factor p16) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16) (MAP1 light chain 3-related protein)
Gene: GABARAPL2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.585

Property	Details
Experiments	26347139, 20562859
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005776 - autophagosome GO:0005829 - cytosol GO:0031410 - cytoplasmic vesicle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 475 Hs			1 117
+	Hs
		305958 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		585063 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		585053 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11
+	Hs
		585068 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		585059 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		183327 MEFV_HUMAN (17-465): 1.68e-112: 351: 30.88		GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00
+	Hs
		183319 MEFV_HUMAN (17-465): 1.68e-112: 351: 30.88		GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27
+	Hs
		183337 MEFV_HUMAN (17-465): 1.68e-112: 351: 30.88		GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21
+	Hs
		1318696 TRIM7_HUMAN (11-450): 4.66e-121: 365: 34.03		MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14
+	Hs
		183333 MEFV_HUMAN (17-465): 1.68e-112: 351: 30.88		MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11
+	Hs
		183338 MEFV_HUMAN (17-465): 1.68e-112: 351: 30.88		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74
+	Hs
		1261101 TRI41_HUMAN (1-44): 3.5e-10: 64.1: 45.83		MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74