Interactor 1: GRIA1 (P19490)
Glutamate receptor 1 (GluR-1) (AMPA-selective glutamate receptor 1) (GluR-A) (GluR-K1) (Glutamate receptor ionotropic, AMPA 1)
Gene: GRIA1

Interactor 2: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.911

The method score is based on:

Property Details
Experiments 8552236, 30975770, 19942860, 21317873, 16338934
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, electron microscopy 3D single particle reconstruction, cosedimentation in solution
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0001540 - amyloid-beta binding
GO:0001919 - regulation of receptor recycling
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
GO:0005783 - endoplasmic reticulum
and 43 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 907
Rn

1 883
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+ Mm
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+ Mm

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Last updated: 15 Jul 2024