Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 26739260, 28863863, 12593667, 19617541, 19946266, 25103407, 25119039, 31925409, 30975770, 19461580, 21317873, 24673938
Identification Methods biochemical, x-ray crystallography, molecular sieving, light scattering, classical fluorescence spectroscopy, cross-linking study, 3D electron microscopy, protein cross-linking with a bifunctional reagent, electron microscopy 3D single particle reconstruction, cosedimentation in solution and 1 others

more...

Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan, Lig_chan~Lig_chan-Glu_bd, Lig_chan~SBP_bac_3, Lig_chan-Glu_bd~Lig_chan-Glu_bd, Lig_chan-Glu_bd~SBP_bac_3, SBP_bac_3~SBP_bac_3
Common GO terms GO:0000149 - SNARE binding
GO:0001540 - amyloid-beta binding
GO:0001919 - regulation of receptor recycling
GO:0004970 - glutamate-gated receptor activity
GO:0004971 - AMPA glutamate receptor activity
and 64 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 883
Rn

1 883
+ Hs
+ Mm
+ Hs
+ Rn
+ Mm
+ Hs
+ Rn
+ Mm
+ Rn
+ Mm
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024