HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: Q99PR9 (Q99PR9)
Voltage-dependent calcium channel gamma-2 subunit
Gene: Cacng2

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36441793
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Lig_chan~PMP22_Claudin, Lig_chan-Glu_bd~PMP22_Claudin
Common GO terms	GO:0032281 - AMPA glutamate receptor complex GO:0098839 - postsynaptic density membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 883 Rn			1 323
+	Rn
		585177 GRIA2_RAT (1-883): 0: 930: 100.00		CCG2_RAT (1-323): 5.37e-141: 403: 99.69
+	Mm
		291990 GRIA2_MOUSE (1-883): 0: 929: 99.89		CCG2_MOUSE (1-323): 5.37e-141: 403: 99.69
+	Hs
		786752 GRIA2_HUMAN (1-883): 0: 931: 99.55		CCG2_HUMAN (1-323): 2.2e-140: 401: 98.45
+	Mm
		621048 GRIA2_MOUSE (1-883): 0: 929: 99.89		CCG3_MOUSE (1-323): 1.21e-121: 353: 70.59
+	Hs
		786719 GRIA1_HUMAN (4-868): 0: 870: 70.09		CCG2_HUMAN (1-323): 2.2e-140: 401: 98.45
+	Rn
		585154 GRIA1_RAT (4-868): 0: 867: 69.75		CCG2_RAT (1-323): 5.37e-141: 403: 99.69
+	Mm
		291989 GRIA1_MOUSE (4-868): 0: 863: 68.82		CCG2_MOUSE (1-323): 5.37e-141: 403: 99.69
+	Hs
		816230 GRIA4_HUMAN (1-848): 0: 850: 73.19		CCG2_HUMAN (1-323): 2.2e-140: 401: 98.45
+	Rn
		585179 GRIA2_RAT (1-883): 0: 930: 100.00		CCG8_RAT (4-323): 7.41e-100: 302: 44.50
+	Mm
		621016 GRIA2_MOUSE (1-883): 0: 929: 99.89		CCG8_MOUSE (4-323): 1.09e-98: 299: 44.04
+	Mm
		620910 GRIA1_MOUSE (4-868): 0: 863: 68.82		CCG3_MOUSE (1-323): 1.21e-121: 353: 70.59
+	Rn
		585156 GRIA1_RAT (4-868): 0: 867: 69.75		CCG8_RAT (4-323): 7.41e-100: 302: 44.50
+	Hs
		786706 GRIA1_HUMAN (4-868): 0: 870: 70.09		CCG8_HUMAN (4-323): 3.24e-96: 292: 46.73
+	Ce
		106308 GLR1_CAEEL (3-845): 0: 605: 36.12		G5EDT2_CAEEL (1-321): 2.88e-94: 285: 19.24