HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: PICK1 (Q9EP80)
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)
Gene: PICK1

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.744

The method score is based on:

Property Details
Experiments 15458844, 20018661, 10340301, 10027300, 17914463, 16055064, 11891216
Identification Methods two hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, nuclear magnetic resonance, pull down
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0008021 - synaptic vesicle
GO:0008092 - cytoskeletal protein binding
GO:0014069 - postsynaptic density
GO:0030425 - dendrite
and 7 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 883
Rn

1 416
+ Mm
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024