HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: SDCB1 (Q9JI92)
Syntenin-1 (Syndecan-binding protein 1)
Gene: Sdcbp

Species: Rattus norvegicus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	0.60	0.586

Property	Details
Experiments	15458844, 11891216
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0035255 - ionotropic glutamate receptor binding GO:0044877 - protein-containing complex binding GO:0098793 - presynapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 883 Rn			1 300
+	Hs
		132764 GRIA2_HUMAN (1-883): 0: 931: 99.55		SDCB1_HUMAN (1-300): 4.8e-99: 294: 89.33
+	Rn
		585196 GRIA3_RAT (2-883): 0: 881: 72.14		SDCB1_RAT (1-300): 3.73e-103: 305: 100.00
+	Hs
		132765 GRIA3_HUMAN (2-883): 0: 883: 71.80		SDCB1_HUMAN (1-300): 4.8e-99: 294: 89.33
+	Rn
		585157 GRIA1_RAT (4-868): 0: 867: 69.75		SDCB1_RAT (1-300): 3.73e-103: 305: 100.00
+	Hs
		132763 GRIA1_HUMAN (4-868): 0: 870: 70.09		SDCB1_HUMAN (1-300): 4.8e-99: 294: 89.33
+	Rn
		585219 GRIA4_RAT (1-848): 0: 851: 74.36		SDCB1_RAT (1-300): 3.73e-103: 305: 100.00
+	Hs
		132771 GRIA4_HUMAN (1-848): 0: 850: 73.19		SDCB1_HUMAN (1-300): 4.8e-99: 294: 89.33
+	Hs
		132839 GRIK2_HUMAN (2-847): 0: 790: 38.75		SDCB1_HUMAN (1-300): 4.8e-99: 294: 89.33
+	Mm
		621019 GRIA2_MOUSE (1-883): 0: 929: 99.89		LNX2_MOUSE (109-296): 1.27e-19: 90.7: 14.11
+	Hs
		786726 GRIA2_HUMAN (1-883): 0: 931: 99.55		DLG4_HUMAN (181-270): 1.28e-15: 79.2: 24.74
+	Mm
		620965 GRIA2_MOUSE (1-883): 0: 929: 99.89		DLG4_MOUSE (181-270): 1.28e-15: 79.2: 24.74
+	Hs
		786757 GRIA3_HUMAN (2-883): 0: 883: 71.80		DLG4_HUMAN (181-270): 1.28e-15: 79.2: 24.74
+	Mm
		620904 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG2_MOUSE (6-288): 3.74e-22: 98.4: 14.24
+	Mm
		1143566 GRIA3_MOUSE (2-883): 0: 881: 71.01		DLG4_MOUSE (181-270): 1.28e-15: 79.2: 24.74
+	Hs
		786696 GRIA1_HUMAN (4-868): 0: 870: 70.09		DLG1_HUMAN (7-200): 8.65e-19: 88.4: 21.61
+	Rn
		585151 GRIA1_RAT (4-868): 0: 867: 69.75		DLG1_RAT (7-200): 2.52e-17: 84.2: 21.61
+	Mm
		620881 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG3_MOUSE (177-288): 3.64e-17: 83.8: 19.33
+	Rn
		585138 GRIA1_RAT (4-868): 0: 867: 69.75		DLG4_RAT (181-270): 1.28e-15: 79.2: 24.74
+	Mm
		620892 GRIA1_MOUSE (4-868): 0: 863: 68.82		DLG4_MOUSE (181-270): 1.28e-15: 79.2: 24.74
+	Mm
		1143565 GRIA4_MOUSE (1-848): 0: 851: 73.19		DLG4_MOUSE (181-270): 1.28e-15: 79.2: 24.74