HitPredict

Interactor 1: MYO2 (P19524)
Myosin-2 (Cell division control protein 66) (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2)
Gene: MYO2

Interactor 2: YPT32 (P51996)
GTP-binding protein YPT32/YPT11 (Rab GTPase YPT32)
Gene: YPT32

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.873

Property	Details
Experiments	18653471, 18221262, 33656555
Identification Methods	two hybrid, pull down, affinity chromatography technology, protein complementation assay
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	DIL~Ras
Common GO terms	GO:0005935 - cellular bud neck GO:0015031 - protein transport GO:0016192 - vesicle-mediated transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1574 Sc			1 222
+	Sc
		585306 MYO2_YEAST (1-1574): 0: 1156: 100.00		YPT31_YEAST (1-222): 1.28e-87: 259: 80.72
+	Sp
		293471 MYO52_SCHPO (2-1568): 0: 927: 35.81		YPT3_SCHPO (7-222): 1.68e-89: 264: 61.29
+	Dm
		51909 A1Z6Z9_DROME (697-1558): 3.05e-46: 185: 14.80		O18335_DROME (4-222): 3.93e-83: 247: 59.82
+	Hs
		914383 MYO5C_HUMAN (1091-1572): 1.18e-21: 105: 9.18		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Hs
		1079976 MYO5B_HUMAN (1041-1570): 2.02e-17: 91.2: 11.41		RB11B_HUMAN (4-222): 2.1e-84: 251: 58.90
+	Hs
		914453 MYO5B_HUMAN (1041-1570): 2.02e-17: 91.2: 11.41		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Rn
		914521 MYO5B_RAT (1041-1570): 6.96e-17: 89.3: 12.02		RB11A_RAT (4-221): 1.75e-84: 251: 58.72
+	Hs
		914486 MYO5A_HUMAN (1245-1568): 1.27e-11: 72: 9.82		RB11A_HUMAN (4-221): 1.75e-84: 251: 58.72
+	Hs
		884614 MYO5B_HUMAN (1041-1570): 2.02e-17: 91.2: 11.41		RAB25_HUMAN (9-202): 8.48e-69: 211: 54.64