HitPredict

Interactor 1: MYO2 (P19524)
Myosin-2 (Cell division control protein 66) (Class V unconventional myosin MYO2) (Type V myosin heavy chain MYO2) (Myosin V MYO2)
Gene: MYO2

Interactor 2: BRE1 (Q07457)
E3 ubiquitin-protein ligase BRE1 (EC 2.3.2.27) (Brefeldin A-sensitivity protein 1) (RING-type E3 ubiquitin transferase BRE1)
Gene: BRE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	21179020
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1574 Sc			1 700
+	Sc
		691283 MYO4_YEAST (1-1086): 0: 955: 58.99		BRE1_YEAST (1-700): 9.24e-50: 187: 100.00
+	Dm
		1303383 MYO7A_DROME (1-982): 0: 901: 33.94		MYSN_DROME (228-666): 6.66e-13: 74.7: 9.46
+	Hs
		724810 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		ROCK1_HUMAN (141-637): 1.52e-25: 115: 13.87
+	Hs
		148460 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		CTRO_HUMAN (137-615): 1.43e-16: 86.6: 10.00
+	Hs
		724686 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		724687 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		MYH10_HUMAN (245-667): 3.3e-16: 85.5: 10.88
+	Hs
		724943 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		725035 MYH9_HUMAN (721-1373): 3.41e-24: 113: 12.24		MYO5C_HUMAN (86-475): 3.22e-12: 72.3: 12.75
+	Rn
		361106 MYH6_RAT (953-1469): 3.83e-18: 93.6: 12.27		MYH6_RAT (4-521): 1.55e-17: 89.7: 10.28
+	Hs
		1268099 MYO5C_HUMAN (1091-1572): 1.18e-21: 105: 9.18		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		725065 MYO5B_HUMAN (1041-1570): 2.02e-17: 91.2: 11.41		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		522585 MYH7_HUMAN (1261-1573): 2.73e-14: 80.8: 8.57		MYH7_HUMAN (4-511): 1.08e-17: 90.1: 10.29
+	Hs
		1268114 MYO5B_HUMAN (1041-1570): 2.02e-17: 91.2: 11.41		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		502901 MYH6_HUMAN (728-1137): 4.2e-16: 86.7: 10.29		MYH3_HUMAN (2-437): 1.4e-12: 73.5: 10.31
+	Hs
		725086 MYO5A_HUMAN (1245-1568): 1.27e-11: 72: 9.82		MYH9_HUMAN (305-666): 1.45e-16: 86.6: 7.69
+	Hs
		528356 MYH6_HUMAN (728-1137): 4.2e-16: 86.7: 10.29		MYH6_HUMAN (291-661): 1.01e-11: 70.9: 10.53
+	Hs
		1268124 MYO5A_HUMAN (1245-1568): 1.27e-11: 72: 9.82		MY18A_HUMAN (76-573): 1.31e-13: 77: 10.67
+	Hs
		522657 MYH7_HUMAN (1261-1573): 2.73e-14: 80.8: 8.57		MYH4_HUMAN (291-661): 7.81e-11: 67.8: 9.74
+	Hs
		1343920 MYO5A_HUMAN (1245-1568): 1.27e-11: 72: 9.82		MYO5C_HUMAN (86-475): 3.22e-12: 72.3: 12.75