HitPredict

Interactor 1: E2AK2 (P19525)
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
Gene: EIF2AK2

Interactor 2: TRBP2 (Q15633)
RISC-loading complex subunit TARBP2 (TAR RNA-binding protein 2) (Trans-activation-responsive RNA-binding protein)
Gene: TARBP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 7568151, 11438532, 14585331, 21903422
Identification Methods two hybrid, affinity chromatography technology, far western blotting, pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains dsrm~dsrm
Common GO terms GO:0003725 - double-stranded RNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 1 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 551
Hs

1 366
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024