Interactor 1: E2AK2 (P19525)
Interferon-induced, double-stranded RNA-activated protein kinase (EC 2.7.11.1) (Eukaryotic translation initiation factor 2-alpha kinase 2) (eIF-2A protein kinase 2) (Interferon-inducible RNA-dependent protein kinase) (P1/eIF-2A protein kinase) (Protein kinase RNA-activated) (PKR) (Protein kinase R) (Tyrosine-protein kinase EIF2AK2) (EC 2.7.10.2) (p68 kinase)
Gene: EIF2AK2

Interactor 2: DUS2L (Q9NX74)
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like (EC 1.3.1.91) (Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2)
Gene: DUS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.54 0.90 0.702

The method score is based on:

Property Details
Experiments 18096616
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains dsrm~dsrm
Common GO terms GO:0003725 - double-stranded RNA binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0140374 - antiviral innate immune response
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024