HitPredict

Interactor 1: MLR1 (P19625)
Myosin regulatory light chain 1
Gene: mlc-1

Interactor 2: MLE (P53014)
Myosin, essential light chain (Myosin light chain alkali)
Gene: mlc-3

Species: Caenorhabditis elegans

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26952210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	EF-hand_6~EF-hand_8
Common GO terms	GO:0005509 - calcium ion binding GO:0005859 - muscle myosin complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 170 Ce			1 153
+	Hs
		409446 ML12A_HUMAN (11-166): 3.27e-66: 201: 46.80		MYL1_HUMAN (1-146): 5.13e-63: 193: 43.54
+	Ce
		585996 MLR2_CAEEL (1-170): 3.34e-62: 191: 99.41		MLE_CAEEL (1-153): 2.42e-62: 190: 100.00
+	Hs
		159559 ML12B_HUMAN (9-166): 6.83e-67: 203: 46.20		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Hs
		624346 MYL9_HUMAN (11-166): 1.35e-66: 202: 46.15		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Hs
		580632 ML12A_HUMAN (11-166): 3.27e-66: 201: 46.80		MYL6_HUMAN (1-147): 5.78e-50: 158: 43.92
+	Hs
		159536 ML12B_HUMAN (9-166): 6.83e-67: 203: 46.20		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	Hs
		538639 MYL9_HUMAN (11-166): 1.35e-66: 202: 46.15		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	Hs
		538637 ML12A_HUMAN (11-166): 3.27e-66: 201: 46.80		MYL6B_HUMAN (1-146): 4.54e-43: 143: 43.54
+	At
		188361 CDPKU_ARATH (1-169): 5.07e-50: 170: 19.54		CML8_ARATH (1-146): 1.45e-49: 157: 28.57
+	At
		483177 CDPKU_ARATH (1-169): 5.07e-50: 170: 19.54		CALM4_ARATH (1-146): 1.82e-45: 147: 33.33
+	At
		886638 CDPKU_ARATH (1-169): 5.07e-50: 170: 19.54		CALM7_ARATH (1-146): 3.55e-45: 146: 34.01
+	At
		976699 CDPKU_ARATH (1-169): 5.07e-50: 170: 19.54		CALM6_ARATH (1-146): 3.67e-45: 146: 34.69
+	At
		989458 CDPK1_ARATH (1-163): 1.32e-46: 161: 22.02		CDPK1_ARATH (69-153): 5.4e-11: 61.4: 22.09
+	Hs
		483903 CALL3_HUMAN (18-88): 6.57e-12: 61.7: 21.33		CALM1_HUMAN (1-146): 3.49e-48: 154: 34.69
+	Hs
		483976 CALL3_HUMAN (18-88): 6.57e-12: 61.7: 21.33		CALM2_HUMAN (1-146): 3.49e-48: 154: 34.69
+	Dm
		417614 MLR_DROME (2-160): 9.72e-22: 89.4: 39.88		MLC1_DROME (24-148): 1.04e-27: 102: 44.53
+	Sp
		998276 MLR1_SCHPO (2-140): 3.34e-16: 73.9: 31.66		MLR4_SCHPO (10-146): 1.61e-23: 91.3: 39.42
+	At
		1104924 CDPK4_ARATH (32-167): 3.2e-11: 62.6: 14.97		CDPK4_ARATH (12-153): 3e-11: 61.8: 18.54
+	At
		1105900 CDPKB_ARATH (98-170): 1.2e-10: 60.7: 23.68		CDPKB_ARATH (69-153): 2.32e-10: 59.4: 20.93
+	Gm
		1196117 Q84P28_SOYBN (13-107): 8.4e-10: 58.4: 17.00		Q84P28_SOYBN (4-94): 4.12e-10: 58.7: 12.09