HitPredict

Interactor 1: SL9A1 (P19634)
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)
Gene: SLC9A1

Interactor 2: CHP3 (Q96BS2)
Calcineurin B homologous protein 3 (Tescalcin) (TSC)
Gene: TESC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

Property	Details
Experiments	12809501, 11696366, 30287853, 31912575
Identification Methods	far western blotting, pull down, affinity chromatography technology, two hybrid, isothermal titration calorimetry, microscale thermophoresis, molecular sieving, fluorescence technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030027 - lamellipodium
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 815 Hs			1 214
+	Hs
		586063 SL9A1_HUMAN (1-815): 0: 823: 100.00		CHP1_HUMAN (1-206): 6.4e-48: 157: 31.63
+	Hs
		212564 SL9A1_HUMAN (1-815): 0: 823: 100.00		CHP2_HUMAN (1-206): 1.65e-45: 151: 24.54
+	Rn
		642813 SL9A1_RAT (1-815): 0: 787: 93.17		CHP2_RAT (10-206): 4.98e-48: 157: 27.45
+	Rn
		642812 SL9A1_RAT (1-815): 0: 787: 93.17		CHP1_RAT (1-206): 1.56e-47: 156: 31.63
+	Rn
		822755 SL9A2_RAT (34-799): 0: 686: 46.38		CHP2_RAT (10-206): 4.98e-48: 157: 27.45
+	Rn
		822754 SL9A2_RAT (34-799): 0: 686: 46.38		CHP1_RAT (1-206): 1.56e-47: 156: 31.63
+	Hs
		1305458 SL9A2_HUMAN (85-799): 0: 660: 47.00		CHP1_HUMAN (1-206): 6.4e-48: 157: 31.63
+	Hs
		212574 SL9A2_HUMAN (85-799): 0: 660: 47.00		CHP2_HUMAN (1-206): 1.65e-45: 151: 24.54
+	Hs
		822764 SL9A3_HUMAN (81-806): 0: 622: 39.03		CHP1_HUMAN (1-206): 6.4e-48: 157: 31.63
+	Hs
		212565 SL9A3_HUMAN (81-806): 0: 622: 39.03		CHP2_HUMAN (1-206): 1.65e-45: 151: 24.54
+	Rn
		642816 SL9A3_RAT (76-806): 0: 614: 37.99		CHP2_RAT (10-206): 4.98e-48: 157: 27.45
+	Rn
		642815 SL9A3_RAT (76-806): 0: 614: 37.99		CHP1_RAT (1-206): 1.56e-47: 156: 31.63
+	Rn
		642819 SL9A4_RAT (54-697): 0: 570: 44.63		CHP2_RAT (10-206): 4.98e-48: 157: 27.45
+	Rn
		642818 SL9A4_RAT (54-697): 0: 570: 44.63		CHP1_RAT (1-206): 1.56e-47: 156: 31.63
+	Hs
		1149580 SL9A4_HUMAN (54-697): 0: 568: 44.92		CHP1_HUMAN (1-206): 6.4e-48: 157: 31.63
+	Hs
		212570 SL9A4_HUMAN (54-697): 0: 568: 44.92		CHP2_HUMAN (1-206): 1.65e-45: 151: 24.54
+	Hs
		1060400 SL9A5_HUMAN (75-713): 7.33e-172: 520: 40.30		CHP1_HUMAN (1-206): 6.4e-48: 157: 31.63
+	Rn
		1194995 SL9A5_RAT (57-715): 9.51e-172: 520: 39.27		CHP2_RAT (10-206): 4.98e-48: 157: 27.45
+	Rn
		895408 SL9A5_RAT (57-715): 9.51e-172: 520: 39.27		CHP1_RAT (1-206): 1.56e-47: 156: 31.63
+	Hs
		212568 SL9A5_HUMAN (75-713): 7.33e-172: 520: 40.30		CHP2_HUMAN (1-206): 1.65e-45: 151: 24.54