Interactor 1: MET8 (P15807)
Siroheme biosynthesis protein MET8 [Includes: Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)]
Gene: MET8
Interactor 2: MET8 (P15807)
Siroheme biosynthesis protein MET8 [Includes: Precorrin-2 dehydrogenase (EC 1.3.1.76); Sirohydrochlorin ferrochelatase (EC 4.99.1.4)]
Gene: MET8
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 0.90 | 0.663 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 18467557 |
| Identification Methods | protein complementation assay, dihydrofolate reductase reconstruction |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | NAD_binding_7~NAD_binding_7, NAD_binding_7~Sirohm_synth_C, NAD_binding_7~Sirohm_synth_M, Sirohm_synth_C~Sirohm_synth_M, Sirohm_synth_M~Sirohm_synth_M |
| Common GO terms | GO:0000103 - sulfate assimilation GO:0004325 - ferrochelatase activity GO:0019354 - siroheme biosynthetic process GO:0043115 - precorrin-2 dehydrogenase activity GO:0051266 - sirohydrochlorin ferrochelatase activity |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
