HitPredict

Interactor 1: PRP9 (P19736)
Pre-mRNA-splicing factor PRP9
Gene: PRP9

Interactor 2: LSM8 (P47093)
U6 snRNA-associated Sm-like protein LSm8
Gene: LSM8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	37968396, 16429126
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	LSM~SF3A3
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0005681 - spliceosomal complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 530 Sc			1 109
+	Sc
		586495 PRP9_YEAST (1-530): 0: 671: 100.00		RUXG_YEAST (2-69): 1.63e-17: 72.4: 21.62
+	Sc
		586509 PRP9_YEAST (1-530): 0: 671: 100.00		LSM3_YEAST (5-76): 5.4e-10: 53.5: 22.22
+	Hs
		912034 SF3A3_HUMAN (2-530): 1.93e-148: 437: 23.02		RUXG_HUMAN (3-69): 6.78e-25: 90.8: 20.29
+	Hs
		68416 SF3A3_HUMAN (2-530): 1.93e-148: 437: 23.02		RUXGL_HUMAN (3-69): 6.48e-23: 85.8: 20.29
+	Hs
		927944 SF3A3_HUMAN (2-530): 1.93e-148: 437: 23.02		RSMN_HUMAN (2-64): 5.94e-17: 74.7: 20.00
+	Hs
		538927 SF3A3_HUMAN (2-530): 1.93e-148: 437: 23.02		RSMB_HUMAN (2-64): 9.82e-17: 74.3: 20.00