HitPredict

Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.755

Property	Details
Experiments	28514442, 27705803, 33961781, 35016035, 35271311, 32707033, 36736316, 23455922
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 342
+	Hs
		902872 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		625294 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		902968 CSK23_HUMAN (1-334): 1.02e-121: 357: 85.03		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		586779 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		586707 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		934199 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		934127 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		1083317 CSK23_HUMAN (1-334): 1.02e-121: 357: 85.03		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		997819 CSK23_HUMAN (1-334): 1.02e-121: 357: 85.03		RBBP4_HUMAN (10-342): 2.39e-68: 221: 13.98
+	Hs
		586657 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		903116 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		792970 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		625202 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82