Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: CSK2B (P67870)
Casein kinase II subunit beta (CK II beta) (Phosvitin) (Protein G5a)
Gene: CSNK2B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.990

The method score is based on:

Property Details
Experiments 14667819, 9571630, 9188720, 24981860, 33961781, 35271311, 23555304, 26496610, 10561590, 27705803, 30279146, 10799509, 32296183, 32707033, 36736316, 21486957, 21988832, 23455922, 7768894, 10094392 and 2 others

more...

Identification Methods two hybrid, affinity chromatography technology, far western blotting, enzymatic study, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach, validated two hybrid, pull down, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CK_II_beta~Pkinase
Common GO terms GO:0000785 - chromatin
GO:0004674 - protein serine/threonine kinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 350
Hs

1 215
+ Hs
+ Mm
+ Bt
+ Hs
+ Hs
+ Hs
+ Dm
+ Ce
+ Dm
+ Sc
+ Sc
+ Sp
+ Sc
+ Sp
+ Dm
+ Sc
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024