HitPredict

Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 16051665
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 2442
+	Hs
		934361 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		625532 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		CBP_HUMAN (1-2442): 0: 1104: 100.00
+	Hs
		586708 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		934128 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		625393 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		998769 MK14_HUMAN (18-343): 1.11e-117: 346: 29.38		EP300_HUMAN (1-2426): 0: 874: 55.06
+	Hs
		586792 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		BRDT_HUMAN (1059-1195): 1.74e-34: 146: 25.55
+	Hs
		586572 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		586761 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Dm
		437070 CSK2A_DROME (7-335): 3.26e-119: 349: 81.46		Q4V5A7_DROME (1059-1356): 3.56e-42: 168: 18.54
+	At
		1106545 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		GTE1_ARATH (1011-1279): 4.44e-42: 162: 19.20
+	Hs
		631394 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Hs
		934182 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		BRD3_HUMAN (1073-1195): 1.36e-33: 143: 30.89
+	Hs
		91522 E7EU96_HUMAN (1-349): 1.27e-123: 362: 81.13		BRD2_HUMAN (1065-1195): 9.64e-34: 143: 30.53
+	Sc
		584705 CSK22_YEAST (8-326): 2.64e-123: 359: 59.69		BDF1_YEAST (1024-1207): 1.45e-32: 139: 21.51
+	Sp
		771122 CSK2A_SCHPO (8-326): 1.44e-117: 344: 64.89		YK82_SCHPO (698-1194): 1.8e-33: 142: 15.18
+	Hs
		297825 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		K0754_HUMAN (1834-2150): 2.41e-10: 68.6: 11.94
+	Sc
		584789 CSK22_YEAST (8-326): 2.64e-123: 359: 59.69		GCN5_YEAST (1110-1192): 5.75e-12: 72.4: 37.35
+	Dm
		437085 CSK2A_DROME (7-335): 3.26e-119: 349: 81.46		Q9VC96_DROME (1044-1195): 1.97e-10: 68.9: 31.98
+	Hs
		1082593 MK14_HUMAN (18-343): 1.11e-117: 346: 29.38		KMT2C_HUMAN (1945-2437): 8.84e-10: 67.1: 13.89