HitPredict

Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: CDC5L (Q99459)
Cell division cycle 5-like protein (Cdc5-like protein) (Pombe cdc5-related protein)
Gene: CDC5L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	26186194, 28514442, 32707033, 23455922
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007049 - cell cycle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 802
+	Hs
		934416 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	Hs
		625571 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		CDC5L_HUMAN (1-802): 0: 756: 100.00
+	At
		955167 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		CDC5L_ARATH (3-800): 3.92e-180: 540: 45.03
+	At
		955169 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		CDC5L_ARATH (3-800): 3.92e-180: 540: 45.03
+	At
		1106379 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		Q9M118_ARATH (3-328): 9.75e-75: 248: 14.16
+	At
		1106306 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MYB39_ARATH (4-349): 2.01e-72: 243: 17.32
+	At
		1106375 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MYB41_ARATH (3-280): 1.32e-68: 229: 16.08
+	At
		1106390 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MYB92_ARATH (5-326): 8.33e-68: 229: 16.82
+	At
		1106572 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		Q94GA6_ARATH (3-145): 2.12e-67: 226: 26.90
+	At
		1106536 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		MYB63_ARATH (3-273): 4.1e-66: 223: 19.64
+	At
		1106398 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		Q9SRB0_ARATH (4-185): 7.66e-63: 217: 19.68
+	At
		96628 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MYB88_ARATH (11-209): 1.82e-61: 217: 24.52
+	At
		1104881 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		MYB6_ARATH (2-172): 1.15e-65: 220: 16.76
+	At
		1106535 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		MB3R5_ARATH (4-276): 4.03e-62: 220: 24.36
+	At
		96630 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		MYB88_ARATH (11-209): 1.82e-61: 217: 24.52
+	At
		96995 MPK6_ARATH (2-337): 5.11e-120: 353: 24.14		F4J1R5_ARATH (4-175): 5.3e-63: 215: 26.52
+	At
		1106297 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MYB56_ARATH (4-128): 6.6e-52: 185: 28.57
+	Hs
		486869 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		MYBB_HUMAN (4-527): 1.91e-47: 182: 16.51
+	At
		1106392 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		WER_ARATH (6-150): 3.83e-51: 179: 28.29
+	At
		1093108 MPK4_ARATH (6-341): 2.39e-122: 358: 27.59		MY115_ARATH (5-86): 2.23e-12: 71.2: 39.02