HitPredict

Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: PRC2C (Q9Y520)
Protein PRRC2C (BAT2 domain-containing protein 1) (HBV X-transactivated gene 2 protein) (HBV XAg-transactivated protein 2) (HLA-B-associated transcript 2-like 2) (Proline-rich and coiled-coil-containing protein 2C)
Gene: PRRC2C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	35271311, 32707033, 23455922
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 350 Hs			1 2896
+	Hs
		934581 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		PRC2C_HUMAN (1-2896): 0: 771: 100.00
+	Hs
		1082653 MK14_HUMAN (18-343): 1.11e-117: 346: 29.38		MUC12_HUMAN (37-2530): 3.99e-68: 260: 8.73
+	Hs
		92118 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		NACAM_HUMAN (47-1172): 1.56e-31: 138: 8.12
+	Hs
		587064 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		625662 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		NCOR2_HUMAN (685-2896): 1.59e-24: 115: 7.48
+	Hs
		586853 CSK22_HUMAN (1-350): 5.04e-136: 392: 100.00		MINK1_HUMAN (253-1019): 3.45e-10: 68.1: 11.95
+	Hs
		934563 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		625528 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		TITIN_HUMAN (1221-2896): 4.19e-20: 101: 7.44
+	Hs
		625642 CDK2_HUMAN (37-331): 1.98e-123: 358: 29.74		SRRM2_HUMAN (10-1337): 2.52e-18: 95.2: 8.28
+	Hs
		297825 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		K0754_HUMAN (785-1391): 2.96e-14: 82: 9.49
+	Hs
		934410 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Hs
		934307 CSK21_HUMAN (1-348): 1.58e-124: 364: 81.36		MINK1_HUMAN (253-1019): 3.45e-10: 68.1: 11.95
+	Sc
		584735 CSK22_YEAST (8-326): 2.64e-123: 359: 59.69		SEC31_YEAST (1809-2249): 1.42e-11: 72.8: 14.56
+	Hs
		1082593 MK14_HUMAN (18-343): 1.11e-117: 346: 29.38		KMT2C_HUMAN (1901-2885): 8.54e-14: 80.6: 9.27
+	Hs
		1082617 MK14_HUMAN (18-343): 1.11e-117: 346: 29.38		CIC_HUMAN (57-1435): 3.5e-10: 68.5: 9.73
+	Sc
		550035 CSK21_YEAST (8-331): 9.02e-107: 319: 55.62		SEC31_YEAST (1809-2249): 1.42e-11: 72.8: 14.56