HitPredict

Interactor 1: ESR1 (P19785)
Estrogen receptor (ER) (ER-alpha) (Estradiol receptor) (Nuclear receptor subfamily 3 group A member 1)
Gene: ESR1

Interactor 2: PRGR (Q00175)
Progesterone receptor (PR) (Nuclear receptor subfamily 3 group C member 3)
Gene: Pgr

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22396492
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Hormone_recep~Hormone_recep, Hormone_recep~zf-C4, zf-C4~zf-C4
Common GO terms GO:0001223 - transcription coactivator binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003707 - nuclear steroid receptor activity
GO:0004879 - nuclear receptor activity
GO:0005496 - steroid binding
and 13 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 599
Mm

1 926
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Last updated: 15 Jul 2024