HitPredict

Interactor 1: ITIH2 (P19823)
Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH2

Interactor 2: TSG6 (P98066)
Tumor necrosis factor-inducible gene 6 protein (EC 3.1.1.-) (Hyaluronate-binding protein) (TNF-stimulated gene 6 protein) (TSG-6) (Tumor necrosis factor alpha-induced protein 6) (TNF alpha-induced protein 6)
Gene: TNFAIP6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	33961781, 24005673
Identification Methods	affinity chromatography technology, surface plasmon resonance, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005540 - hyaluronic acid binding GO:0005576 - extracellular region GO:0030212 - hyaluronan metabolic process
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 946 Hs			1 277
+	Hs
		957099 ITIH3_HUMAN (53-940): 0: 994: 39.04		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00
+	Hs
		587399 ITIH1_HUMAN (54-940): 0: 963: 39.11		TSG6_HUMAN (12-277): 2.95e-95: 283: 100.00