HitPredict

Interactor 1: ITIH2 (P19823)
Inter-alpha-trypsin inhibitor heavy chain H2 (ITI heavy chain H2) (ITI-HC2) (Inter-alpha-inhibitor heavy chain 2) (Inter-alpha-trypsin inhibitor complex component II) (Serum-derived hyaluronan-associated protein) (SHAP)
Gene: ITIH2

Interactor 2: CEA21 (Q3KPI0)
Carcinoembryonic antigen-related cell adhesion molecule 21
Gene: CEACAM21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.80	0.770

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	V-set~VWA
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 946 Hs			1 293
+	Hs
		587334 ITIH2_HUMAN (1-946): 0: 1149: 100.00		CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56
+	Hs
		685270 CA2D3_HUMAN (306-520): 2.09e-47: 186: 19.55		CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56
+	Hs
		685226 CA2D1_HUMAN (308-499): 6.03e-42: 168: 21.54		CEAM8_HUMAN (5-253): 2.17e-20: 91.4: 15.56
+	Hs
		509863 COEA1_HUMAN (300-490): 2.45e-32: 138: 18.37		PSG1_HUMAN (5-232): 5.08e-21: 94.1: 18.18