HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: PRDX2 (P32119)
Peroxiredoxin-2 (EC 1.11.1.24) (Natural killer cell-enhancing factor B) (NKEF-B) (PRP) (Thiol-specific antioxidant protein) (TSA) (Thioredoxin peroxidase 1) (Thioredoxin-dependent peroxide reductase 1) (Thioredoxin-dependent peroxiredoxin 2)
Gene: PRDX2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	25609649
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0043066 - negative regulation of apoptotic process
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 198
+	Hs
		587545 NFKB1_HUMAN (1-968): 0: 796: 100.00		PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78
+	Hs
		965096 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		PRDX1_HUMAN (1-197): 7.49e-100: 288: 77.78
+	Hs
		670917 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45
+	Hs
		670682 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13
+	Hs
		671019 Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41		PRDX3_HUMAN (2-198): 8.33e-101: 293: 63.45
+	Dm
		1276696 NFKB1_DROME (712-963): 2.24e-22: 105: 14.44		PRDX2_DROME (5-195): 6.74e-95: 276: 70.16
+	Hs
		670777 ASB3_HUMAN (452-812): 5.04e-31: 130: 18.16		PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13
+	Hs
		670764 Q9H4D1_HUMAN (622-789): 9.95e-18: 90.6: 24.41		PRDX6_HUMAN (4-196): 1.88e-67: 207: 29.13