Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.59 1.00 0.771

The method score is based on:

Property Details
Experiments 11425860
Identification Methods enzymatic study, in-gel kinase assay, anti tag coimmunoprecipitation
Interaction Type direct interaction, phosphorylation reaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Pkinase, Ank_2~Pkinase
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
and 2 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 968
Hs

1 420
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Last updated: 15 Jul 2024