HitPredict

Interactor 1: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Interactor 2: MTPN (P58546)
Myotrophin (Protein V-1)
Gene: MTPN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	11971907
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~RHD_dimer
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0071260 - cellular response to mechanical stimulus
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 968 Hs			1 118
+	Hs
		587690 NFKB1_HUMAN (1-968): 0: 796: 100.00		BARD1_HUMAN (31-118): 2.19e-31: 118: 27.27
+	Hs
		276140 NFKB1_HUMAN (1-968): 0: 796: 100.00		PSD10_HUMAN (64-118): 4.1e-15: 69.9: 21.82
+	Hs
		587628 NFKB1_HUMAN (1-968): 0: 796: 100.00		ANKH1_HUMAN (2-93): 1.32e-10: 58.9: 35.87
+	Hs
		885777 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		MTPN_HUMAN (1-118): 5.13e-42: 135: 100.00
+	Hs
		885778 REL_HUMAN (35-484): 6.21e-110: 354: 33.91		MTPN_HUMAN (1-118): 5.13e-42: 135: 100.00
+	Hs
		978869 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		BARD1_HUMAN (31-118): 2.19e-31: 118: 27.27
+	Hs
		1349604 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		RAI14_HUMAN (2-99): 2.66e-26: 103: 27.72
+	Mm
		103608 ANK3_MOUSE (381-967): 1e-99: 346: 14.24		ANK2_MOUSE (1-87): 3.16e-30: 114: 31.03
+	Mm
		103591 ANK3_MOUSE (381-967): 1e-99: 346: 14.24		ANK3_MOUSE (1-87): 3.56e-25: 100: 26.44
+	Hs
		161473 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		MYPT1_HUMAN (4-87): 2.11e-16: 75.5: 25.00
+	Hs
		276172 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		PSD10_HUMAN (64-118): 4.1e-15: 69.9: 21.82
+	Hs
		978897 TF65_HUMAN (28-420): 6.77e-116: 368: 34.41		EHMT1_HUMAN (2-49): 3.3e-09: 54.8: 22.92
+	Hs
		167036 ANR50_HUMAN (360-930): 1.1e-108: 369: 13.96		ANR28_HUMAN (12-93): 8.44e-09: 53.5: 34.15
+	Hs
		225123 ANK1_HUMAN (539-967): 7.32e-78: 281: 16.84		MYPT2_HUMAN (4-87): 6.52e-20: 85.3: 27.38
+	Hs
		862028 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		DAPK1_HUMAN (2-87): 6.05e-24: 96.8: 27.91
+	Hs
		883461 RIPK4_HUMAN (478-862): 1.18e-61: 227: 21.00		MTPN_HUMAN (1-118): 5.13e-42: 135: 100.00
+	Hs
		225134 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		MYPT2_HUMAN (4-87): 6.52e-20: 85.3: 27.38
+	Hs
		639798 IKBA_HUMAN (485-767): 1.18e-66: 228: 35.45		BARD1_HUMAN (31-118): 2.19e-31: 118: 27.27
+	Hs
		166913 ANK2_HUMAN (63-670): 1.17e-72: 266: 12.37		ANR28_HUMAN (12-93): 8.44e-09: 53.5: 34.15