HitPredict

Interactor 1: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Interactor 2: ACS2 (P52910)
Acetyl-coenzyme A synthetase 2 (EC 6.2.1.1) (Acetate--CoA ligase 2) (Acyl-activating enzyme 2)
Gene: ACS2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 572 Sc			1 683
+	Hs
		500150 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		ACS2L_HUMAN (37-674): 0: 655: 46.25
+	Ec
		458095 CH60_ECOLI (23-556): 5.78e-172: 500: 53.56		PRPE_ECOLI (39-674): 7.79e-178: 522: 36.66
+	Hs
		499998 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		ACSF2_HUMAN (55-652): 3.7e-161: 479: 20.33
+	Hs
		499835 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		ACSM5_HUMAN (41-650): 2.91e-161: 478: 22.49
+	Ec
		457979 CH60_ECOLI (23-556): 5.78e-172: 500: 53.56		LCFA_ECOLI (89-653): 3.29e-157: 467: 21.32
+	Hs
		499796 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		ACSF3_HUMAN (275-643): 9.79e-23: 104: 27.12