HitPredict

Interactor 1: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Interactor 2: CDH1 (P53197)
APC/C activator protein CDH1 (CDC20 homolog 1) (Homolog of CDC twenty 1)
Gene: CDH1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.50	0.543

Property	Details
Experiments	11805837, 22189709
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 572 Sc			1 566
+	Sc
		587964 HSP60_YEAST (1-548): 0: 542: 100.00		CDC20_YEAST (16-549): 3.27e-105: 330: 28.26
+	Hs
		1306738 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		FZR1_HUMAN (30-566): 8.72e-96: 302: 36.58
+	Hs
		1306645 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		TBL1Y_HUMAN (55-544): 8.19e-94: 298: 14.01
+	Hs
		499599 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		LIS1_HUMAN (288-565): 3.67e-78: 254: 17.06
+	Hs
		792942 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		LIS1_HUMAN (288-565): 3.67e-78: 254: 17.06
+	Hs
		499716 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		CDC20_HUMAN (13-457): 6.59e-59: 206: 16.59
+	Hs
		1017427 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		CDC20_HUMAN (13-457): 6.59e-59: 206: 16.59
+	Hs
		499666 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		WDR5_HUMAN (371-566): 2.98e-53: 186: 19.80
+	Hs
		826632 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		CDC20_HUMAN (13-457): 6.59e-59: 206: 16.59
+	Hs
		903467 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR5_HUMAN (371-566): 2.98e-53: 186: 19.80
+	Hs
		1202777 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR5B_HUMAN (372-566): 2e-50: 178: 17.86
+	Hs
		826601 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		WDR5_HUMAN (371-566): 2.98e-53: 186: 19.80
+	Hs
		1306704 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		NLE1_HUMAN (43-412): 3.31e-46: 170: 10.11
+	Hs
		499671 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		921697 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		921038 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		GBB1_HUMAN (372-559): 9.12e-27: 113: 19.19
+	Hs
		826605 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		GBB2_HUMAN (372-547): 1.81e-31: 126: 21.11
+	Hs
		826604 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		GBB1_HUMAN (372-559): 9.12e-27: 113: 19.19
+	Hs
		134793 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		PEX7_HUMAN (353-553): 1.61e-13: 73.6: 28.02
+	Hs
		134772 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		PEX7_HUMAN (353-553): 1.61e-13: 73.6: 28.02