HitPredict

Interactor 1: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Interactor 2: WDR59 (Q03897)
Maintenance of telomere capping protein 5 (SEH-associated protein 3)
Gene: MTC5

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	11805837, 25073740
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 572 Sc			1 1148
+	Hs
		499599 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Sc
		588120 HSP60_YEAST (1-548): 0: 542: 100.00		COPB2_YEAST (2-364): 3.6e-36: 150: 11.14
+	Hs
		792942 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		LIS1_HUMAN (154-488): 3.85e-46: 173: 12.24
+	Ce
		837579 CH60_CAEEL (5-554): 9.83e-180: 520: 56.62		LIN53_CAEEL (23-187): 2.27e-24: 109: 16.02
+	Hs
		283005 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		CIAO1_HUMAN (164-399): 2.77e-26: 113: 13.69
+	Sc
		588281 HSP60_YEAST (1-548): 0: 542: 100.00		YP247_YEAST (63-415): 1.28e-15: 83.3: 16.67
+	Hs
		1306704 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		NLE1_HUMAN (388-681): 3.05e-24: 109: 7.47
+	Hs
		1301634 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR24_HUMAN (3-175): 8.12e-21: 100: 13.74
+	Hs
		282850 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		CIAO1_HUMAN (164-399): 2.77e-26: 113: 13.69
+	Hs
		1240450 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		POC1A_HUMAN (286-515): 2.27e-17: 87.7: 9.26
+	Hs
		1306644 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		GRWD1_HUMAN (143-329): 3.41e-17: 87.6: 15.18
+	Hs
		1162299 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR59_HUMAN (2-169): 1.31e-15: 84.2: 8.29
+	At
		597192 CPNB1_ARATH (23-561): 2.82e-178: 518: 44.75		PEX7_ARATH (118-340): 2.11e-14: 77.6: 16.60
+	Hs
		499671 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		GBB2_HUMAN (295-492): 6.76e-13: 73.4: 10.00
+	Hs
		921697 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		GBB2_HUMAN (295-492): 6.76e-13: 73.4: 10.00
+	Hs
		1083362 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		RBBP7_HUMAN (53-354): 1.26e-12: 73.3: 15.24
+	Hs
		499666 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59
+	Hs
		1202777 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR5B_HUMAN (1-96): 5.82e-10: 64.1: 13.73
+	Hs
		903467 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59
+	Hs
		826601 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		WDR5_HUMAN (1-97): 8.99e-10: 63.7: 13.59