HitPredict

Interactor 1: AT2B1 (P20020)
Plasma membrane calcium-transporting ATPase 1 (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 1) (PMCA1) (Plasma membrane calcium pump isoform 1)
Gene: ATP2B1

Interactor 2: NPTN (Q9Y639)
Neuroplastin (Stromal cell-derived receptor 1) (SDR-1)
Gene: NPTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001772 - immunological synapse GO:0001818 - negative regulation of cytokine production GO:0042734 - presynaptic membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1220 Hs			1 398
+	Hs
		588550 AT2B1_HUMAN (1-1220): 0: 1275: 100.00		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		966910 AT2B2_HUMAN (1-1220): 0: 1238: 78.62		NPTN_HUMAN (1-398): 2.03e-77: 246: 100.00
+	Hs
		1086562 AT2B3_HUMAN (1-1220): 0: 1228: 79.02		NPTN_HUMAN (1-398): 2.03e-77: 246: 100.00
+	Hs
		726158 AT2B2_HUMAN (1-1220): 0: 1238: 78.62		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		619304 AT2B4_HUMAN (7-1220): 0: 1207: 73.15		NPTN_HUMAN (1-398): 2.03e-77: 246: 100.00
+	Hs
		726228 AT2B3_HUMAN (1-1220): 0: 1228: 79.02		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		619205 AT2B4_HUMAN (7-1220): 0: 1207: 73.15		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		164055 AT2A1_HUMAN (50-1066): 0: 787: 25.12		NPTN_HUMAN (1-398): 2.03e-77: 246: 100.00
+	Hs
		163761 AT2A1_HUMAN (50-1066): 0: 787: 25.12		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		393077 AT1A1_HUMAN (41-1082): 0: 770: 22.46		BASI_HUMAN (10-398): 5.47e-66: 216: 38.33
+	Hs
		1031158 AT2A3_HUMAN (50-1065): 0: 781: 25.25		PTK7_HUMAN (151-378): 4.46e-23: 103: 16.39