Interactor 1: PRP4 (P20053)
U4/U6 small nuclear ribonucleoprotein PRP4 (Pre-mRNA-processing protein 4)
Gene: PRP4

Interactor 2: PRP8 (P33334)
Pre-mRNA-splicing factor 8
Gene: PRP8

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 11805826, 16429126, 16373487, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PRO8NT~WD40, PROCN~WD40, PRP8_domainIV~WD40
Common GO terms GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
GO:0017070 - U6 snRNA binding
GO:0046540 - U4/U6 x U5 tri-snRNP complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 465
Sc

1 2413
+ Hs
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024